Co trimoxazole Monograph for Professionals Drugs. Class Sulfonamides. VA Class AM9. 00. CAS Number 8. 06. Brands Bactrim, Bactrim DS, Septra, Septra DS, Sulfatrim. Introduction. Antibacterial fixed combination of sulfamethoxazole intermediate acting sulfonamide and trimethoprim both sulfamethoxazole and trimethoprim are folate antagonist anti infectives. Uses for Co trimoxazole. Acute Otitis Media. Treatment of acute otitis media AOM in adults and children caused by susceptible Streptococcus pneumoniae or Haemophilus influenzae. Not a drug of first choice considered an alternative for treatment of AOM, especially for those with type I penicillin hypersensitivity. I/51nXLJRmemL._SR600%2C315_PIWhiteStrip%2CBottomLeft%2C0%2C35_SCLZZZZZZZ_.jpg' alt='Paediatric Dosage Handbook' title='Paediatric Dosage Handbook' />Because amoxicillin resistant S. AOM who fail to respond to amoxicillin. Data are limited regarding safety of repeated use of co trimoxazole in pediatric patients lt 2 years of age the drug should not be administered prophylactically or for prolonged periods for treatment of AOM in any age group. GI Infections. Treatment of travelers diarrhea caused by susceptible enterotoxigenic Escherichia coli. PubMed comprises more than 27 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full. Pharmacy. The role of the Department of Pharmacy is to provide pharmaceutical care to patients to contribute to the development of excellent paediatric practitioners. PDF printable version of 4. Hepatitis B of the 10th edition of the Handbook. This chapter has been amended on July 2016. Virology 4. 5. 2 Clinical features. Use this calculator to work out the gestation at birth, if all you know is the EDD Enter EDD Must be in future Changing the EDD will change the. Completion of medicines reconciliation when patients are transferred between care settings reduces the risk of patients experiencing harm from their medication. Canadian Paediatric Society Protecting and promoting the health and wellbeing of children and youth. Replacement therapy with oral fluids and electrolytes may be sufficient for mild to moderate disease 1. Fluoroquinolones ciprofloxacin, levofloxacin, norfloxacin, ofloxacin usually drugs of choice when treatment indicated 1. Prevention of travelers diarrhea in individuals traveling forrelatively short periods to areas where enterotoxigenic E. U1Sk2J0qM/hqdefault.jpg' alt='Paediatric Dosage Handbook' title='Paediatric Dosage Handbook' />Pharmaceutical Press publishes essential pharmacy books and online information for the science and practice of pharmacy. More than 4,500 ebooks and many book collections, including archive collections of critical historical material, as well as publisher and topical collections. PDF printable version of 4. Hepatitis A of the 10th edition of the Handbook. Virology 4. 4. 2 Clinical features 4. Epidemiology 4. 4. Vaccines. Shigella are known to be susceptible to the drug. CDC and others do not recommend anti infective prophylaxis in most individuals traveling to areas of risk 1. If prophylaxis is used e. HIV infection, a fluoroquinolone ciprofloxacin, levofloxacin, ofloxacin, norfloxacin is preferred. Resistance to co trimoxazole is common in many tropical areas. Treatment of enteritis caused by susceptible Shigella flexneri or S. Treatment of dysentery caused by enteroinvasive E. EIEC. 2. 86 AAP suggests that an oral anti infective e. Treatment of diarrhea caused by enterotoxigenic E. ETEC in travelers to resource limited countries. Optimal therapy not established, but AAP suggests that use of co trimoxazole, azithromycin, or ciprofloxacin be considered if diarrhea is severe or intractable and if in vitro testing indicates the causative organism is susceptible. A parenteral regimen should be used if systemic infection is suspected. Role of anti infectives in treatment of hemorrhagic colitis caused by shiga toxin producing E. STEC formerly known as enterohemorrhagic E. E. coli 0. 15. 7 H7. Treatment of GI infections caused by Yersinia enterocolitica or Y. These infections usually are self limited, but IDSA, AAP, and others recommend anti infectives for severe infections, when septicemia or other invasive disease occurs, and in immunocompromised patients. Other than decreasing the duration of fecal excretion of the organism, a clinical benefit of anti infectives in management of enterocolitis, pseudoappendicitis syndrome, or mesenteric adenitis caused by Yersinia has not been established. Respiratory Tract Infections. Treatment of acute exacerbation of chronic bronchitis caused by susceptible S. H. influenzae. 13. A drug of choice for treatment of upper respiratory tract infections and bronchitis caused by H. G or penicillin V for treatment of respiratory tract infections caused by S. Alternative for treatment of infections caused by Legionella micdadei L. L. pneumophila. 1. Urinary Tract Infections UTIsTreatment of UTIs caused by susceptible E. Klebsiella, Enterobacter, Morganella morganii, Proteus mirabilis, or P. A drug of choice for empiric treatment of acute uncomplicated UTIs. Brucellosis. Treatment of brucellosis alternative when tetracyclines are contraindicated e. Used alone or in conjunction with other anti infectives e. Burkholderia Infections. Treatment of infections caused by Burkholderia cepacia. Co trimoxazole considered drug of choice ceftazidime, chloramphenicol, or imipenem are alternatives. Treatment of melioidosis caused by susceptible B. Ceftazidime or imipenem monotherapy may be preferred. B. pseudomallei is difficult to eradicate and relapse of melioidosis is common. Cholera. Treatment of cholera caused by Vibrio cholerae. Alternative to tetracyclines used as an adjunct to fluid and electrolyte replacement in moderate to severe disease. Cyclospora Infections. Treatment of infections caused by Cyclospora cayetanensis. The drug of choice. Granuloma Inguinale DonovanosisTreatment of granuloma inguinale donovanosis caused by Calymmatobacterium granulomatis. CDC recommends doxycycline or co trimoxazole. Isosporiasis. Treatment of isosporiasis caused by Isospora belli. The drug of choice. Listeria Infections. Treatment of infections caused by Listeria monocytogenes 1. Mycobacterial Infections. Treatment of cutaneous infections caused by Mycobacterium marinum 1. Nocardia Infections. Treatment of infections caused by Nocardia, including N. N. brasiliensis, and N. Drugs of choice are co trimoxazole. Pertussis. Treatment of the catarrhal stage of pertussis to potentially ameliorate the disease and reduce its communicability. Recommended by CDC, AAP, and others as an alternative to erythromycin. Prevention of pertussis in household and other close contacts e. Alternative to erythromycin. Ps3 Emulator For Pc there. Plague. Has been used for postexposure prophylaxis of plague. Although recommended by CDC and others for such prophylaxis in infants and children lt 8 years of age,1. Most experts e. g., CDC, AAP, the US Working Group on Civilian Biodefense, US Army Medical Research Institute of Infectious Diseases recommend oral ciprofloxacin or doxycycline for postexposure prophylaxis in adults and most children. Postexposure prophylaxis recommended after high risk exposures to plague, including close exposure to individuals with naturally occurring plague, during unprotected travel in active epizootic or epidemic areas, or laboratory exposure to viable Yersinia pestis. Has been used for treatment of plague, but appears to be less effective than other anti infectives used for treatment of the disease e. Because of lack of efficacy, some experts state that co trimoxazole should not be used for the treatment of pneumonic plague. Pneumocystis jiroveci Pneumocystis carinii Pneumonia. Treatment of Pneumocystis jiroveci formerly Pneumocystis carinii pneumonia PCP. Initial drug of choice for most patients with PCP,1. HIV infected individuals. Prevention of initial episodes of PCP primary prophylaxis in immunocompromised individuals at increased risk, including HIV infected individuals. Drug of choice. 1. Long term suppressive or chronic maintenance therapy secondary prophylaxis to prevent recurrence following an initial PCP episode in immunocompromised patients, including HIV infected individuals. Drug of choice. 1. Toxoplasmosis. Prevention of toxoplasmosis encephalitis primary prophylaxis in HIV infected adults, adolescents, and children who are seropositive for Toxoplasma Ig. G antibody. 1. 19. Drug of choice. 2. Not recommended for long term suppressive or chronic maintenance therapy secondary prophylaxis to prevent recurrence of toxoplasmosis encephalitis regimen of choice for secondary prophylaxis of toxoplasmosis is sulfadiazine and pyrimethamine with leucovorin. Typhoid Fever and Other Salmonella Infections. Alternative for treatment of typhoid fever enteric fever caused by susceptible Salmonella typhi. WHO Documents on child health. Maternal, newborn, child and adolescent health. An evidence map of social, behavioural and community engagement interventions for reproductive, maternal, newborn and child health. Assessing and managing children at primary health care facilities to prevent overweight and obesity in the context of the double burden of malnutrition. Updates for the integrated management of childhood illness IMCI Guideline. Better hospital care for children. Improving quality of paediatric care at first level referral hospitals in Angola, Ethiopia, Kyrgyzstan and Tajikistan final technical report 2. Levels and trends in child mortality report 2. Estimates Developed by the UN Inter agency Group for Child Mortality Estimation. Managing possible serious bacterial infection in young infants when referral is not feasible. Guidelines and WHOUNICEF recommendations for implementation. Programme reporting standards for sexual, reproductive, maternal, newborn, child and adolescent health. WHO recommendations on child health. A systematic review of the effectiveness of shortening Integrated Management of Childhood Illness guidelines training. Final report. Child and adolescent health and development progress report 2. Complementary feeding counselling. A training course. Countdown to 2. 01. The 2. 00. 8 report. Global action plan for the prevention and control of pneumonia GAPPReport of an informal consultation, La Mainaz, Gex, France, 57 March 2. Indicators for assessing infant and young child feeding practices. Part I definition. Introducing zinc in a diarrhoeal control programme. Guide to conducting formative research. Manual for the health care of children in humanitarian emergencies. Report of a technical consultation on IMCI training approaches and pre service IMCIGeneva, Switzerland, 1. November, 2. 00. 7Strengthening action to improve feeding of infants and young children 6 2. Report of proceedings, Geneva, 6 9 October 2. A review of the technical basis for the control of conditions associated with GAS infections. A simple solution. TIME October 1. 6, 2. CAH progress report 2. Call for support for appropriate infant and young child feeding in the current Asian emergency, and caution about unnecessary use of milk products. WHO, UNICEF, ICRC, IFRC statement. CHERG abstraction exercise. CHERG estimates of the burden of malaria morbidity in Africa in children under the age of five years. CHERG estimates of the burden of mortality directly attributable to malaria for children under 5 years of age in Africa for the year 2. Child health in the community Community IMCIBriefing package for facilitators. Clinical management of acute diarrhoea. WHOUnicef joint statement. Consultation on child health in complex emergencies. Meeting report. Dengue, dengue haemorrhagic fever and dengue shock syndrome in the context of the Integrated Management of Childhood Illness. Diarrhoea treatment guidelines including new recommendations for the use of ORS and zinc supplementation for clinic based healthcare workers. Effective teaching. A guide for educating healthcare providers. Epidemiology and management of common skin diseases in children in developing countries. Ethambutol efficacy and toxicity. Literature review and recommendations for daily and intermittent dosage in children. Family and community practices that promote child survival, growth and development. A review of the evidence. Group A streptococcal vaccine development. Current status and issues of relevance to less developed countries. Guidance for national tuberculosis programmes on the management of tuberculosis in children Guiding principles for feeding non breastfed children 6 2. How to address psychosocial reactions to catastrophe. Implementing the new recommendations on the clinical management of diarrhoea. Guidelines for policy makers and programme managers. Indoor air pollution and child health in Pakistan. Report of a seminar, Karachi, Pakistan, 2. September 2. 00. 5 Infant and Young Child Feeding Counselling. An Integrated Course. Informal consultation on clinical use of oxygen. Management of pneumonia in community settings. WHOUNICEF Joint Statement. Management of sick children by community health workers. Intervention models and programme examples. Mental health and psychosocial wellbeing among children in severe food shortage situations. Model IMCI handbook Integrated management of childhood illness Oral rehydration salts. Production of the new ORSPneumonia the forgotten killer of children. Serious childhood problems in countries with limited resources. TBHIV A clinical manual. Technical updates of the guidelines on the IMCIEvidence and recommendations for further adaptations. The current evidence for the burden of group A streptococcal diseases. The importance of caregiver child interactions for the survival and healthy development of young children. A review. Urinary tract infections in infants and children in developing countries in the context of IMCIWHO, UNICEF, and SCN informal consultation on community based management of severe malnutrition in children. SCN Nutrition Policy Paper No.